FDA Safety Information for Celexa and Saphris
Celexa (citalopram hydrobromide): Drug Safety Communication – Abnormal Heart Rhythms Associated with High Doses
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Issue: FDA notified healthcare professionals and patients that the antidepressant Celexa (citalopram hydrobromide) should no longer be used at doses greater than 40 mg per day because it can cause abnormal changes in the electrical activity of the heart.
Celexa (citalopram hydrobromide) is in a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs).
Saphris (asenapine maleate): Drug Safety Communication – Serious Allergic Reactions
Issue: FDA notified healthcare professionals and patients that serious allergic reactions have been reported with the use of Saphris (asenapine maleate). The Contraindications, Warnings and Precautions, Adverse Reactions, and Patient Counseling Information sections have been revised to include information about type I hypersensitivity reactions which may include anaphylaxis, angioedema, low blood pressure, rapid heart rate, swollen tongue, difficulty breathing, wheezing, or rash. In several cases, these reactions occurred after the first dose.
Saphris (asenapine maleate) is used to treat symptoms of schizophrenia and bipolar disorder